• Parenteral Excipient (SOLBIOTE™)
  • Additives for Culture Medium

SOLBIOTE™|TREHALOSE SG

TREHALOSE SG, an injectable-grade saccharide excipient, prevents cells and protein from damage, stabilizing nucleotides.

Trehalose is a non-reducing disaccharide consisting of two glucose molecules linked by an α,α‒1,1 bond. TREHALOSE SG is a highly purified dihydrate crystalline with a low endotoxin specification and used for parenteral formulations.

Key Solutions

For Biopharmaceuticals


TREHALOSE SG is unique in its high glass transition temperature (Tg, T’g) and remarkable acid tolerance as well as heat stability, showing no Maillard reaction when heated in solutions containing amino acids. TREHALOSE SG provides solutions for stabilizing protein structures when proteins are lyophilized or frozen, and is also known to prevent cells and liposomes from damage during freezing and thawing.

Applications

  • Stabilization of antibodies, peptides, and vaccines for injection

  • Stabilization of exosomes

  • Preservation of platelets

Related Technical Articles:

■ ‘Trehalose is enabling life-changing protein therapeutics and exosomes’, biopharmadealmakers, Sep. 2022 nature research

For Culture Medium


TREHALOSE SG protects cells by stabilizing the cell membranes and is used as a protective agent in cryopreservation media.

Applications

  • Additive for culture medium

Product Info

Purity

≧99.0% (Trehalose)

Endotoxin

<0.3 EU/g

Packaging

•1kg PE bag

•20kg PE bag in a carton box

•20kg PE bag in a plastic container

Regulatory Approval

•JP

•USP-HF

•Ph. Eur.

•CP

•US DMF Type IV

•China DMF (F20170000105 (A))

Other

•Kosher

•Halal

Other SOLBIOTE™ Portfolio

→ MALTOSE PH

Documentation

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