Endotoxin Removal Service
Do you have any troubles on endotoxin
(Lipopolysaccharides, LPS) control?
NAGASE can apply its “Endotoxin Removal Technique” to your issues and provide the best solution.
NAGASE can offer endotoxin-removal services for a variety of materials from which low endotoxin levels are a challenge to achieve or can directly provide low-endotoxin materials to you from our catalog.
Endotoxin removal service
Example of studies for endotoxin removal
- Proteins
- Poly-
saccharides - Synthetic polymers
- Peptides
- Enzymes
Our specialty is to remove endotoxins from water-soluble natural polymers including high viscous materials.
When you have materials to remove endotoxin from, please feel free to contact us via “Inquiries”.
NAGASE will help you with Materialsʼ endotoxin removal studies and Endotoxin-removal services for a variety of materials from which low endotoxin levels are a challenge to achieve including commercialization support as needed.
*There may be materials from which endotoxins are difficult to remove; our service welcomes the most challenging of projects.
*"Removal" does not mean that the product's endotoxin level is 0.
Flow of endotoxin removal service
The above chart is the standard flow of our endotoxin removal study service. We will be flexible on your request.
This Web site, brochure and product specifications/standards (“This Web site, etc”) may be subject to change without notice. This Web site, etc has been prepared in good faith based on our data and study, however, we assume no liability for such Information or use of such Information, including but not limited to, warranty for no infringement of intellectual property rights of third party, compliance of applicable laws and regulations.Please evaluate the suitability for your use, purpose, and conditions on your own responsibilities.
Our purification technique
Nagase ChemteX, which is a core manufacturer of NAGASE group, has developed endotoxin removal agents utilizing its fine chemical organic synthesis technologies in collaboration with Kumamoto University*1.
*1 Patent Number: WO2017018524
Application examples
- Implanted medical devices
(artificial skin, artificial bone, artificial vessel, etc.) - Hemostatic agents
- Wound-covering materials
- Anti-adhesive materials
- Scaffolds for regenerative medicine
- Pharmaceutical additives etc.
- Implanted medical devices
Since endotoxin causes inflammation and cell death, materials used for the above purposes are required to have low endotoxin levels.