Lp-PLA2
Summary of the Test Item
• High serum Lp-PLA2 activity is a risk factor for coronary artery disease.
• Guidelines*1 recommend the Lp-PLA2 test to predict the risk of future onset of cardiovascular diseases.
• Particularly in the United States and China, the market for Lp-PLA2 tests is growing.
| *1 | 2014 – International Atherosclerosis Society 2016 – American Heart Association/American Stroke Association 2017 – American Association of Clinical Endocrinologists and American College of Endocrinology |
Nagase Diagnostics Solutions
Reagent for Enzymatic Assay of Lp-PLA2 Materials and Methods
The Lp-PLA2 Activity Assay Reagent (Enzymatic Assay)*2, *3 by Nagase Diagnostics (formerly Asahi Kasei Pharma Corporation Diagnostics Division) is characterized by its versatility, which makes it highly convenient, and its endogenous substrate.
*2 Novel enzymatic method for assaying Lp-PLA2 in serum. Clinica Chimica Acta; International Journal of Clinical Chemistry vol. 481 (2018): 184-188. Yamaura, Saki et al. DOI: 10.1016/j.cca.2018.03.012
*3 Patented in Japan, the United States, and China
Versatility | Nagase Diagnostics | Chemical method | ELISA |
|---|---|---|---|
Number of reagents | 2 | 2–3 | Many |
Calibration points | 2 | 2–5 | Many |
Compatibility with general purpose automated biochemical analyzers | Yes | Partially | No |
Reagent stability | ≥12 months | NA | NA |
The reagent for the enzymatic assay by Nagase Diagnostics is stable for 12 months or longer under refrigeration.
We simplify reagent development by supplying the components, materials, and production procedures.
Measurement Principle
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